Bill Murray, Geena Davis, and Randy Quaid play three friends who decide to make a quick score by robbing a bank and taking off for a faraway island. They set up an elaborate, almost playful plan, but every step of the way either Quaid screws it up or New York City just won't let them go, allowing detective Jason Robards to get closer and closer. With the money strapped to their bodies, the hapless trio gets caught up in a series of misadventures as they try desperately to get to the airport.