Struck by lightning in midair, a 747 has begun hurtling its passengers towards their doom. With the pilot and copilot dead, there is no one to safely guide the plane down. Laurie (Jackson), the head flight attendant, and a passenger, Brett (Marino) take it upon themselves to try and save the plane. They are relieved to find that the auto-pilot can safely land them, but their relief doesn't last long; they soon determine that the auto-pilot can't lock in a suitable airport where the jumbo jet can land. Meanwhile, the Air Force is deciding whether they should just shoot the plane down over a deserted area rather than have it crash into a city.