Variety - 03/16/1988
"...A barnstorming performance by Dennis Quaid..."
A washed-up writer/college professor discovers one day that someone has slipped him a poison, leaving him with only 48 hours to live. He spends his final days searching for his murderer. A remake of the classic film noir.
Description by Buena Vista Home Entertainment:
Time. It's running out for Dexter Cornell (Dennis Quaid). He has just 24 hours to find out who poisoned him ... and why. In his bizarre and deadly search, everyone has a secret. Everyone is a suspect. Even the woman (Meg Ryan) who loves him. Directed by Rocky Morton and Annabel Jankel, creators of superstar "Max Headroom," D.O.A. pulsates with explosive action and sizzling performances by Quaid and Ryan, two people who find themselves suddenly living on the edge. It's a night on the run, filled with fear, danger ... and passion.
Sleepwalking through the academia, an alcoholic professor spends more time drinking than grading papers or writing new novels. The once promising writer gets a wake up call when he discovers he has only a few days to live after being poisoned. With a perky co-ed, he is driven to find his killer.