Morrie (Matthew Perry, (Friends) is the keeper of all things family related, including his siblings. In this comedic foray into sibling relationships, Morrie's little brother Jay (Ben Foster, 3:10 to Yuma, X-Men: The Last Stand) is beyond peculiar, homeless and humorously, but clinically, depressed. His beautiful sister Ida (Ginnifer Goodwin, "Big Love") is a promiscuous insomniac and sometime photographer that is starved for attention. Morrie's wife Betty (Lauren Graham, "Gilmore Girls") has waited patiently for seven years for their hard work to pay off so they can start a family. Morrie's life is unraveling. As his family's antics infuriate his boss and neighbor, his dreams of success are quickly destroyed. Morrie gets a wake-up call and he comes to realize that the people who really care for him will stand by his side no matter what.